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TRANSIL® Intestinal Absorption Kit

A ready-to-use kit for rapid in vitro assessment of drugs' ability to cross the intestinal epithelium

A novel ready-to-use kit designed for rapid assessment of drug candidates' ability to cross the intestinal epithelium. The kit only requires the addition of drug candidates to the microtiter wells followed by a 2-minute incubation. The affinity of the drug candidate is a measurement of its passive transport in the gastrointestinal (GI) tract.

Benefits

  • Fast, requiring only 2 minutes for incubation.
  • Accurate. Measures the affinity of the drug candidate to biological membrane. Captures permeability differences that result from different ionization states of drug candidates, enabling prediction of the fraction absorbed.
  • Reliable with highly reproducible results, and robust correlation to vesicle dialysis.
  • Ready-to-use format plated in 96-well or ready-to-use tubes in strips of 8. Kit requires only addition of test material, 2-minute incubation, and quantification.
  • Flexible. Adaptable to automation.

Product Information

 

Product Number Product Name Format
TMP-0100-0096 Transil® Intestinal Absorption Kit 96-well plate
TMP-0100-1196 Transil® Intestinal Absorption Kit 96-well (strips)
                                                                                                                                                                      

RELATED DOCUMENTS

TRANSIL Membrane Permeability Kits Fact Sheet

TRANSIL Membrane Permeability Kits Fact Sheet
TRANSIL Intestinal Absorption Kit User Manual
TRANSIL Intestinal Absorption Kit Quick Reference Card
TRANSIL References
 

 

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