Category: DNA Templates

Computational and Experimental Study of Turbo-Organomagnesium Amide Reagents: Cubane Aggregates as Reactive Intermediates in Pummerer Coupling

The dynamic equilibria of organomagnesium reagents are recognized to be very complicated, and the relative reactivity of their parts is poorly understood. Herein, a mix of DFT calculations and kinetic experiments is employed to analyze the detailed response mechanism of the Pummerer coupling between sulfoxides and turbo-organomagnesium amides. Among the varied aggregates studied, unprecedented heterometallic

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Identification of Immunohistochemical Reagents for In Situ Protein Expression Analysis of Coronavirus-associated Changes in Human Tissues

We studied the suitability of commercially accessible monoclonal antibodies (mAbs) for the immunohistochemical (IHC) detection of extreme acute respiratory syndrome coronavirus 2 (SARS-CoV2) in normal archival specimens. Antibodies had been screened on HEK293 cells transfected with viral nucleoprotein, S1 subunit and S2 subunit of spike protein and on untransfected cells, in addition to a panel

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